Five weeks of supplementation with plant sterols/stanols softgels in combination with lifestyle changes may reduce total cholesterol levels by 7.4%.
Numerous clinical trials in controlled settings have reported that daily consumption of 1.5 to 3 grams of phytosterols/-stanols from foods can reduce total cholesterol levels by eight to 17%, representing a signficant reduction in the risk of cardiovascular disease.
The new study adds to these findings and reveals that four dietary supplement softgel capsules per day may be effective for similar reductions when incorporated in the National Cholesterol Education Program (NCEP) Therapeutic Lifestyle Changes (TLC) diet.
«The daily incorporation of four dietary supplement softgel capsules (two with each of two meals), providing esterified plant sterols/stanols 1.8 g/d (sterol/stanol esters -2.9 g/d) into the NCEP TLC diet, a dosage that is within the range (1-3 g) for which the response is fairly linear produced favorable changes in atherogenic lipoprotein cholesterol levels in subjects whith hypercholesterolemia similar to those expected based on previous meta-analyses», wrote the researchers.
«The long-term plant sterol/stanol use would be expected to decrease the risk for cardiovascular disease,» they concluded.