Short-term supplementation with vitamin E may support the function of cells lining blood cells from potential damage during the increase in blood sugar levels after eating, says a new study.
Five days of supplementation with a gamma-tocopherol-rich mixture of
tocopherols maintained vascular endothelial function – the function of
the cells lining blood vessels, according to findings.
The vitamin E supplement was also associated with supporting blood flow
in the arteries and a reduction in increases of malondialdehyde (MDA – a
reactive carbonyl compound and a well-established marker of oxidative
stress).
«This study demonstrates that short-term gamma-tocopherol-rich mixture
of tocopherols supplementation in healthy men maintains vascular
endothelial function that is otherwise impaired by postprandial
hyperglycemia likely by decreasing lipid peroxidation without affecting
inflammator responses,» report researchers.
The researchers recruited 15 health men with an average age of 22
participate in their randomized, crossover study. The men were randomly
assigned to receive the vitamin E supplement or nor supplement for five
days prior to fasting and then receiving 75 grams of glucose.
The vitamin E supplement provided 500 milligrams of gamma-tocopherol, 60
mg of alpha-tocopherol, 170 mg of delta-tocopherol, and 9 mg of
beta-tocopherol.
Results showed that the glucose test produced significant increases in
MDA levels, and decreases of 30-44% in blood flow, as measured by
brachial artery flow-mediated dilation (FMD). However, vitamin E
supplementation prevented such changes. The researchers also report for
the first time the vascular endothelial function was maintained in the
men after consuming the vitamin E supplement.
«Our findings support that gamma-tocopherol-rich mixture of tocopherols
is beneficial for maintaining vascular endothelial function in healthy
young men,» wrote the researchers.
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Source: Nutraingredients