01 Apr Lutein, zeaxanthin plus omega-3 shows benefits for AMD sufferers
A combination of lutein, zeaxanthin and omega-3 long-chain polyunsaturated fatty acids may boost the pigment in the retina and help people with age-related macular degeneration (AMD), says new data from Germany.
Results of the randomized, double-blind, placebo.controlled and parallel trial indicated that daily doses of lutein, zeaxanthin, EPA and DHA increased the optical density of the macular pigment in people suffering from dry AMD.
“Supplementation with omega-3 resulted in drecreased levels of AA while EPA and DHA levels increased, with even more favorable fatty acid profile changes in the higher dose group”, according to the researchers. “This susggests that higher doses of EPA and DHA may improve retina function by promoting pro-inflammatory signaling pathways. This beneficial outcome could also have a positive impact on the link which has been established between pathogenesis of AMD and atherogenesis.
The study adds to an ever growing body of science supporting the vital role of the carotenoids lutein and zeaxanthin for eye health. Both are found in high levels in the macula, a yellow sport of about five millimeters diameter on the retina.
These compounds are the only carotenoids capable of filtering the ahrmful blue light than can damage cells in the eye, the rods and the cones.
A thin macular pigment can allow the blue light throught and destroy
the cells. Maintaining high levels of both carotenoids, and therefore
the macular pigment, is a valid approach to maintaining eye health and
reducing the risk of diseases, like age-related macular degeneration