Daily supplements of conjugated linoleic acid (CLA) may benefit intestinal health, suggests new data from a study with Crohn’s disease.
Results of a pilot study with 13 people with Crohn’s disease indicated that daily supplements with CLA were associated with a suppression of pro-inflammatory compounds, decreased disease activity and an improved quality of life.
Crohn’s disease is a chronic relapsing immune-inflammatory disease involving the gastrointestinal tract. The causes of the disease are largely unknown although there is increasing evidence of an interplay between genetic factors, environmental triggers and immune dysregulation.
«CLA represents a promising new supportive intervention for gut inflammation,» wrote the researchers.
«The present study has shed new light on the clinical potential of this compound and provided insights on the possible mechanisms of immune modulation targeted by CLA in the human system.»
CLA is a fatty acid naturally present in ruminant meat and dairy products. Due to changes in the Western diet, average intake of CLA has fallen; if the fat is removed from a dairy product to make a low fat version that will be acceptable to consumers, CLA is removed along with it.
The ingredient was recently highlighted as a nutrient with a «key» role to play in the global weight management market. The ingredient is most often found as a mixture of isomers: cis-9, trans-11 and trans-10, cis-12
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Source: Nutraingredients