Heart disease is the leading cause of death for haemodialysis patients, and oxidative stress and hyperhomocysteinaemia are thought to be contributing factors.

In addition, antioxidant depletion and lipid peroxidation are among the main causes of increased atherosclerosis risk in such patients.

Based on this, researchers from Sabzevar University of Medical Sciences analysed the status of antioxidant and anti-homocysteine vitamins linked to heart disease in haemodialysis patients.

Insufficient intake

They assesed 75 patients – 33 men and 42 women – for height, wiegth, food frequency and food intake for a minimun of two days (one non-dialysis and one dialysis day).

«According to our findings, receiving all nutrients excpt vitamin B12 was less than recommended in haemodialysis patients. Intake of vit A, E, C and B9 in men were 29%, 7%, 52%, 32% respectively and in women were 32%, 7,5%, 76% and 33% respectively».

At the same time, previous studies involving haemodialysis patients have shown that their levels of antioxidant vitamins C and E are tipically low.

Dialysis and its detriments

This was due in part to vitamin depletion during dialysis. Antioxidant vitamin E levels in haemodialysis patients were lowered due to free radicals produced during dialysis.

A and E against mortality

The study states: «It seems that low intake of vitamins A and E is due to reduced oil consumption and high-fat dairy products. On the other hand, hypercholesterolemia and hyperlipidemia are common in haemodialysis patients».

It added that there was a direct link between regular intake of water-soluble vitamins and reduced risk of death from heart disease in haemodialysis patients.
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Source: William Reed Business Media