Isoflavone-rich supplement boost artery health: Study

A dietary supplement rich in isoflavones may improve the function of arteries in stroke patients, according to new research from Hong Kong. The study is said to be the first randomised controlled trial investigating the effects of isoflavone supplements on improving the blood flow in the arm?s main artery in cardiovascular disease patients. A daily 80 mg dose of isoflavones was associated with a one per cent increase in flow-mediated dilation (FMD), the measure of a blood vessel’s healthy ability to relax, according to findings published today in the European Heart Journal. «These findings may have important implications for the use of isoflavone for secondary prevention in patients with cardiovascular disease, on top of conventional treatments,» wrote the authors in their EHJ paper. Isoflavones from soy have been shown to provide a number of health benefits, including the promotion of heart health and the maintenance of bone health in post-menopausal women. They have also been studied for their role in cancer prevention and slowing down the ageing process in peri-menopausal women, and isoflavone-rich supplements have proved to be a popular alternative to HRT for those wishing to control menopause symptoms without resorting to drugs. Supplementation with isoflavones was also associated with decreases in the levels of a protein called high-sensitivity C-reactive protein (CRP). This protein is a marker of inflammation and is reported to be an independent predictor of cardiovascular-related events. «These findings suggested that isoflavone[s] alleviated vascular inflammatory stress and was an important component that mediated the reversal of endothelial dysfunction in this group of patients,» wrote the authors. Source: European Heart Journal Published online ahead of print, doi:10.1093/eurheartj/ehn409 ?Reduction of C-reactive protein with isoflavone supplement reverses endothelial dysfunction in patients with ischaemic stroke? Authors: Y.-H. Chan, K.-K. Lau, K.-H.Yiu, S.-W. Li, H.-T. Chan, D.Y.-T. Fong, S. Tam, C-P. Lau, H.-F. Tse
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