A dietary supplement rich in isoflavones may improve the function of
arteries in stroke patients, according to new research from Hong Kong.
The study is said to be the first randomised controlled trial
investigating the effects of isoflavone supplements on improving the
blood flow in the arm?s main artery in cardiovascular disease patients. A
daily 80 mg dose of isoflavones was associated with a one per cent
increase in flow-mediated dilation (FMD), the measure of a blood
vessel’s healthy ability to relax, according to findings published today
in the European Heart Journal. «These findings may have important
implications for the use of isoflavone for secondary prevention in
patients with cardiovascular disease, on top of conventional
treatments,» wrote the authors in their EHJ paper. Isoflavones from soy
have been shown to provide a number of health benefits, including the
promotion of heart health and the maintenance of bone health in
post-menopausal women. They have also been studied for their role in
cancer prevention and slowing down the ageing process in peri-menopausal
women, and isoflavone-rich supplements have proved to be a popular
alternative to HRT for those wishing to control menopause symptoms
without resorting to drugs. Supplementation with isoflavones was also
associated with decreases in the levels of a protein called
high-sensitivity C-reactive protein (CRP). This protein is a marker of
inflammation and is reported to be an independent predictor of
cardiovascular-related events. «These findings suggested that
isoflavone[s] alleviated vascular inflammatory stress and was an
important component that mediated the reversal of endothelial
dysfunction in this group of patients,» wrote the authors. Source:
European Heart Journal Published online ahead of print,
doi:10.1093/eurheartj/ehn409 ?Reduction of C-reactive protein with
isoflavone supplement reverses endothelial dysfunction in patients with
ischaemic stroke? Authors: Y.-H. Chan, K.-K. Lau, K.-H.Yiu, S.-W. Li,
H.-T. Chan, D.Y.-T. Fong, S. Tam, C-P. Lau, H.-F. Tse
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Source: Nutraingredients.com