The potential heart health benefits of conjugated linoleic acid (CLA)
may be linked to its ability to alter protein expression in platelets,
says a new study that may explain some of the anti-atherogenic effects
of the fatty acids.
Supplementation with CLA (cis-9, trans-11) resulted for three month was
associated with alterations in 40 proteins in the platelets of 40
overweight but healthy people participating in a double-blind,
randomized, placebo-controlled, paralle-group trial.
«This comprehensive study of platelet proteomics in a dietary trial of a
80:20 cis-9, trans-11 CLA blend revealed many intriguing findings
worthy of further investigation,» worte the researchers.
«The focal adhesion pathway appeared an important mechanism of action
which could contribute to the previously reported antiatherogenic
effects of dietary cis-9, trans-11 CLA.»
CLA is a fatty acid naturally present in ruminant meat and dairy
products. Due to changes in the Western diet, average intake of CLA has
fallen; if the fat is removed from a dairy product to make a low fat
version that will be acceptable to consumers, CLA is removed along with
it.
Using proteomic techniques the researchers deduced that CLA
supplementation produced «significant alterations in levels of 46 spots
of which 40 were identified».
Category: Productos
Source: Nutraingredients